NOD2 gene mutations in ulcerative colitis: useless or misunderstood?
نویسندگان
چکیده
منابع مشابه
NOD2/CARD15 gene, Crohn’s Disease, mutation, Inflammatory bowel disease, Ulcerative colitis.
سابقه و هدف: ژن NOD2/CARD15 واقع در ناحیه کروموزومی(IBD1)16q12 به عنوان اولین ژن همراه با بیماریهای التهابی روده، به خصوص بیماری کرون مطرح شده است. بسیاری مطالعات همراهی متفاوتی از جهشهای این ژن با بیماریهای التهابی روده را در جمعیتهای مختلف گزارش کرده اند. در این مطالعه، فراوانی سه جهش شایع ژن CARD15 را در بیماران ایرانی مبتلا به بیماریهای التهابی روده، در مقایسه با افراد شاهد بررسی نموده ایم...
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ژورنال
عنوان ژورنال: International Journal of Colorectal Disease
سال: 2014
ISSN: 0179-1958,1432-1262
DOI: 10.1007/s00384-014-1850-x